Published As:
US8409410
Title:
Conductivity sensor device comprising diamond film with at least one nanopore or micropore
Value Drivers by Geography
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PCT Application Office Action Grant
United States
Grant
Japan
Grant
Rest of the World
Patent PDF
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Figure 1 - US8409410
Priority Date
15
Nov
10
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Abstract:
Sensor device for ion channel recordings; liquid-liquid measurements and resistive pulse particle counting comprising; at least one sensor element; the element comprising a diamond thin film substrate and a pore which is a nanopore or a micropore included in the substrate. This device may be used in analysis, for instance the device may be used for single molecule detection of an apialyte (e.g. DNA), for the analysis of interactions between a sensor element and an analyte, for the detection of pore forming entities, or for the determination of ion transfer.
Claim 1:
A sensor device for an application selected from ion channel recordings; liquid-liquid based sensors and resistive pulse particle counting, the sensor device comprising; at least one sensor element, the element comprising a diamond thin film substrate, a surface of which is chemically modified; and a pore which is a nanopore or a micropore included in the substrate; wherein the diamond thin film substrate has a templated or layered structure wherein the layered structure comprises layers of diamond of differing conductivities, and wherein the sensor device further comprises two electrodes positioned on opposite sides of the diamond thin film substrate and configured to measure a current within the pore or to measure a voltage across the pore.