Published As:
DE10161899
Title:
New fusion protein, useful for treating Hodgkin's disease, comprises a ligand specific for an antigen-presenting cell and a cell-damaging domain
Value Drivers by Geography
Seller defined
PCT Application Office Action Grant
Rest of the World
Germany
Patent PDF
Figure
New fusion protein, useful for treating Hodgkin's disease, comprises a ligand specific for an antigen-presenting cell and a cell-damaging domain
Priority Date
17
Dec
01
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Abstract:
Novel Fusion Proteins according to the invention are able to target antigen-presenting cells and to destroy them either directly or by attracting T cells.
Claim 1:
Fusion Proteins, wherein they comprise a specific ligand for an antigen-presenting cell, ligand is selected from CD153, TNF or it region and at least one cell-damaging region selected from GTPase, endotoxin, Vibrio Cholera toxin, protease subtilisin, HLA-B7, CD81, CD86, or microtubule-binding regions of neuronal proteins gephyrin, Tau or MID-1.