Published As:
DE19937512
Title:
For the rapid sequencing of genomes the DNA is linearized automatically and at reduced costs with a mixture of proteases
Value Drivers by Geography
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PCT Application Office Action Grant
Rest of the World
Germany
Patent PDF
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For the rapid sequencing of genomes the DNA is linearized automatically and at reduced costs with a mixture of proteases
Priority Date
09
Aug
99
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Abstract:
A method for fast multiparallel genome sequencing of linearized or stretched DNA, which is ordered on a plate by physical, optical methods.
Claim 1:
Method for fast genome sequencing, wherein two ends of ordered-on-a-plate stretched DNA sequence will be moved in order to reach optimal linearization or stretching and the resulting stretched DNA sequence will be determined multiparallely by physical optical methods; thereby the DNA sequence will be linearized through ligation of its two ends to synthetic DNA sequences, which are bound to moving substrates.