SYSTEM&METHOD FOR ESTIMATING SUBSTANCE CONCENTRATIONS IN BODILY FLUIDS
This invention relates to systems and methods for estimating substance concentrations in bodily fluids. Particularly preferred embodiments of the present invention relate to systems and methods whereby substance concentrations in blood can be optically estimated non-invasively and in vivo
1. A method for estimating the optical response of a subject comprising blood, the method comprising: forming a model whereby the spectral response of a subject to incident light can be estimated, the model including a plurality of parameters, each parameter corresponding to the influence on the spectral response of a respective biochemical substance; directing light of a known spectral content at the subject; detecting the spectral response of the subject to the light; and repeatedly performing the steps of: i. modelling the spectral response of the subject to the light by means of the model; ii. comparing the modelled spectral response with the detected response; and iii. altering the model in dependence on that comparison by varying one or more of the said parameters.